FlavoNAC provides an orthomolecular combination of specific antioxidants targeting REDOX, REDOX signalling, mitochondria homeostasis and ROS control.
Our health starts with mitochondria health. Mitochondria are often referred to as the powerhouses of the cell. Mitochondria are known to generate approximately 90% of cellular reactive oxygen species (ROS). The imbalance between mitochondrial ROS production and removal due decreased antioxidants defense activity results in oxidative stress (OS), which leads to oxidative damage that affects cellular components such as lipids, DNA, and proteins1 (Tirichen 2021). Redox is a process of oxidation-reduction, which are complimentary processes. Redox- dependent processes influence most cellular functions, such as differentiation, proliferation, and apoptosis. Therefore, Redox is important for the regulation of mitochondrial function2, 3, 4 (Handy 2012; Mailloux 2014), (Zuo 2022). Redox signalling is important for cardiovascular health5 (Madamanchi 2013)
Alpinia galanga (Greater Galangal) is an ayurvedic herb rich in phenolic compounds with antioxidant properties6 (Mahae, 2009)
NAC (N-Acetyl Cysteine) is an important antioxidant and a precursor for glutathione. NAC is also essential for reducing oxidative damage and mitochondrial dysregulation7 (Banaclocha 2022). NAC is also important for lung health affected by increased numbers of reactive oxygen species such as in the case of COPD (ROS)8 (Dekhuijzen 2006)
Hesperidin, an antioxidant flavonoid, attenuates altered Redox homeostasis9 (Kumar 2020). Important for lung health problems including lung fibrosis, asthma, chronic obstructive pulmonary disease (COPD), acute respiratory distress syndrome (ARDS), pulmonary fibrosis, emphysema, and other respiratory diseases10 (Hosawi 2023). Hesperidin functions as an ergogenic aid by increasing endothelial function, inhibits ROS production, decreases production and plasma levels of pro-inflammatory markers11 (Imperatrice 2022)
Quercetin is well researched bioactive flavonoid, known for its anti-inflammatory, antihypertensive, vasodilator effects, anti-obesity, anti-hypercholesterolemic and anti-atherosclerotic activities12 (David 2016). Quercetin modulates intra-mitochondrial redox status and protects against mitochondrial damage13 (Oliviera 2015)
Did you know? Alpinia galanga is a plant in the ginger family revered in Indian and Arabian medicine.