Magnesium-threonate is a unique supplement derived from the L-threonate form of magnesium. It’s a relatively new form of supplemental magnesium discovered in 2010 that helps restore optimal magnesium levels in the body. Magnesium is involved in more than 300 essential biochemical processes, making it critical for overall health.
Unlike other magnesium supplements, magnesium-threonate can cross the blood-brain barrier (BBB). This ability may enhance cognitive health more effectively and support other health outcomes, like sleep quality, stress, anxiety, and more.
Provita Nutrition Magnesium Threonate contains Magtein, the clinically studied and patented form of Magnesium-threonate provided by the American company AIDP Inc.
Potential Health Benefits of Magnesium Threonate
Magnesium is well-known for its vital role in overall health. Although research is still limited, emerging studies suggest that magnesium L-threonate may offer a range of health benefits, including the following:
- Alzheimer’s disease and cognitive enhancement: Magnesium-threonate’s effect on cognitive health may be due to its impact on sleep and reduce neurodegeneration associated with Alzheimer’s by enhancing the ability of neurons to form new connections (synaptic plasticity). In human study, it has improved deep sleep, supporting memory retention and learning. 4 Other human research has shown that it improves cognitive ability. Still, these results are preliminary, and more research in humans is needed.
- Anxiety and depression: Magnesium may influence gamma-aminobutyric acid (GABA) neurotransmitters, promoting relaxation and a sense of calm. Magnesium deficiency is also often linked with increased anxiety levels. One study reported improved stress and anxiety levels with magnesium-threonate compared to a placebo. Early research also suggests magnesium may help ease depression. 8 Further study is needed to confirm the results.
- Sleep quality: Magnesium influences multiple aspects of sleep and plays a role in the hypothalamic-pituitary-adrenocortical (HPA) axis, which governs stress and sleep. It is an essential cofactor in the body’s melatonin production, which helps you fall asleep. It also regulates GABA to encourage relaxation and calmness. One study observed better sleep quality and improved daytime alertness, coordination, and balance with 1,000 milligrams (mg) of magnesium-threonate daily. Notably, it increased deep sleep, the most restorative and rejuvenating sleep period.
- Attention-deficit hyperactivity disorder (ADHD) and autism: Some research indicates individuals with ADHD have lower circulating magnesium levels. One study observed a 25% reduction in ADHD symptoms with magnesium L-threonate supplementation for 12 weeks. A magnesium deficiency has also been observed in children suffering from autism. Treatment with Magnesium Threonate associated with Vitamin B6 resulted in improvement of the symptoms of the disease.
How Does Magnesium L-Threonate Work?
Many of the potential health benefits of magnesium-threonate may be related to its ability to cross the blood-brain barrier. L-threonate is a compound found in cerebrospinal fluid, which may explain its unique ability to cross the blood brain barrier (BBB). Once it reaches your brain, Magnesium-threonate may support synaptic plasticity, learning, memory, and neuronal function.
What is in Magnesium Threonate?
Ingredients/vegetable capsule:
Magnesium from 695 mg of magnesium L-threonate |
50 mg/ 13,3% VNR * |
L-glutamic acid |
50 mg |
Vitamin C (calcium ascorbate) |
15 mg / 18,75% VNR * |
Vitamin D3 (cholecalciferol), 100 IU |
2,5 mcg / 50%VNR * |
Microcrystalline cellulose |
Ascorbyl palmitate |
Vegetable capsule: hydroxypropyl methylcellulose |
*NRV = Nutritional Reference Value according to Regulation 1169/20211
Does not contain: artificial colors, preservatives or sweeteners, dairy products, wheat, gluten, yeasts, soy, corn, eggs, nuts or GMOs.
Provita Nutrition & Health Inc., 1102-1225 Kingsway Ave, Port Coquitlam, BC, V3C 1S2, CANADA
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